The other day I noticed a strange annoying behavior using this approach: Each time I opened the application I was working on in the new tab, my builder session was expired. This behavior wasn’t related to the APEX version: it happened with my 4.2 installation running on a VBox as well as with my local installation running 4.1. I was rather puzzled, as I didn’t change anything on my local installation.
Here is what caused it (thanks to Christian Neumüller for explaining):
I ran into the so-called APEX Listener favicon-bug: On my 4.1 installation I was working on a new theme, build entirely from scratch, and on my 4.2 installation, I was playing around with a mobile application. What both applications (or better: themes) had in common: the lack of a favicon reference in the page template. One other thing both environments had in common: an APEX Listener stand-alone installation. Looks like the Listener tries to resolve a favicon location each time, and when not found, redirection the favicon request to the “webservers” root (the favicons default location). With the APEX Listener the “root” gets redirected to yourserver:port/apex, which is causing a reset of the session id.
Adding a favicon to your page template(s) HEAD section solves the problem.
Make sure you’ve got an image file at the specified location. I could reproduce the problem with APEXListener versions 1.1.4 and 2.0.
I was promised, the issue will be addressed in one of the coming versions of the APEX Listener.
Source Article from http://rokitta.blogspot.com/2012/12/apex-listener-favicon-bug-issue.html
APEX Listener favicon bug issue
Oracle & Apex Geekery
And another thing …